Aspartimide Formation in Peptide Synthesis
Aspartimide Formation in Solid-Phase Peptide Synthesis (SPPS) What is Aspartimide Formation? Aspartimide formation is a well-documented side reaction in Solid-Phase Peptide Synthesis (SPPS) that can compromise the integrity and yield of the desired peptide product. This side reaction is particularly concerning because it can occur under both basic and acidic conditions, affecting various stages of … Read more